Alan Carbajo
Machine Learning Researcher in Virology
I'm a researcher working at the intersection of artificial intelligence and virology. My main project so far: a curated, 58,046-genome dataset spanning 15 virus families, and neural networks trained on raw k-mer frequency that predict whether a virus can infect humans, then get interrogated to find out which sequence motifs actually drove that call. I currently work with Dr. Phil Pellett at Wayne State University School of Medicine in Detroit.
What I'm chasing
Most of my work centers on one question: can you tell whether a virus infects humans just by looking at its genome? I built a dataset and a set of models to test that, and then spent most of my time trying to figure out why the models say what they say, which is where the interesting biology shows up.
My model kept flagging HHV-6 as non-human. It turns out it was picking up something real: HHV-6 integrates into host telomeres, a trick almost no other human herpesvirus uses.
- 01 Predicting human host-compatibility straight from raw genome sequence
- 02 Curating a 58,046-genome, 15-family dataset labeled for host range
- 03 Ablating k-mers to map which motifs actually drive a prediction
- 04 Tracking SARS-CoV-2's genomic drift toward human adaptation since 2019
Toolkit
Machine Learning & AI
ML Techniques
Frameworks & Libraries
Natural Language Processing
Computer Vision
Virology & Genomics
Molecular Virology
Immunology
Bioinformatics
Comparative Genomics
Engineering
Languages
Web
Cloud & HPC
Published work
Sequence based virus host prediction: a curated dataset and generalizable framework for training artificial intelligence to identify viruses of humans
Alan L. Carbajo Jr., Taylor A. Vensko, Philip E. Pellett — Virus Evolution, Vol. 12, Issue 1, veag009 · Feb 2026
Presentations
SOMBRA: A System for Operational Modeling of Biological Replication and Adaptation
International Herpes Workshop · 2024
Modeling Novel Proteins of Mutant Human Cytomegalovirus
International Herpes Workshop · 2023
MambaVirus
Wayne State University School of Medicine, Graduate Student Research Presentation Day